Hypocholesterolemia in children and adolescents with β-thalassemia intermedia
نویسندگان
چکیده
Low plasma levels of total cholesterol (TC) with or without hypertriglyceridemia have been frequently described in a variety of hematologic disorders in which anemia is a prominent feature.2,3 It is well established that β-thalassemia is associated with changes in plasma lipids and lipoproteins. In β-thalassemia major, low cholesterol levels caused by a significant reduction of both low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) levels have been consistently reported, whereas reports on triglycerides (TG) levels were discordant. TC and LDL-C seemed similarly decreased in β-thalassemia trait carriers compared with controls, whereas HDL-C and TG blood levels were usually not modified.4-12
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